1.Du, S., Long Q.*, Zhou, Y.,…Liu, X*.(2026). Transplantation of encapsulated mitochondria alleviates dysfunction in mitochondrial and Parkinson's disease models. Cell, 189(10):2821-2833. (Science, Nature News, Nature Genetics、Cell Metabolism专文评述, 新华社通稿)

2.Hu, Z., Yang, L., Zhang, M.,…Liu, X*. (2024). A novel protein CYTB-187AA encoded by the mitochondrial gene CYTB modulates mammalian early development. Cell Metabolism, 36(7):1586-1597.e7. (Cell Metabolism当期专文评述)

3.Ying, Z., Xiang G., Zheng, L., …Liu, X*. (2018). Short-term mitochondrial permeability transition pore opening modulates histone lysine methylation at the early phase of somatic cell reprogramming. Cell Metabolism, 28(6):935-945.

4.Ying, Z., Chen K., Zheng, L., …Liu, X*. (2016). Transient activation of mitoflashes modulates Nanog at the early phase of somatic cell reprogramming. Cell Metabolism, 23(1):220-226.

5.Li, L., Chen, K., Wang, T., …Liu, X*. (2020). Glis1 facilitates induction of pluripotency via an epigenome-metabolome-epigenome signaling cascade. Nature Metabolism 2(9):882-892. (ESI 高被引论文Biology&Biochemistry Top1%)

6.Ying, Z.*, Xin, Y., Liu, Z.,……Liu, X*. (2025). The mitochondrial unfolded protein response inhibits pluripotency acquisition and mesenchymal-to-epithelial transition in somatic cell reprogramming. Nature Metabolism 7(5):940-951. (Nature Metabolism当期专文评述，Nature Collection“A year of stem cell and developmental biology”)

7.Long, Q., Zhou, Y., Wu, H., …Liu, X*. (2021). Phase separation drives the self-assembly of mitochondrial nucleoids for transcriptional modulation. Nature Structural & Molecular Biology 28(11):900-908.

8.Li, W., Long, Q., Wu, H., …Liu, X*. (2022). Nuclear localization of mitochondrial TCA cycle enzymes modulates pluripotency via histone acetylation. Nature Communications, 13(1):7414. (Editors’ Highlights)

9.Yang, L., Ruan, Z., Lin, X., …Liu, X*. (2024). NAD+ dependent UPRmt activation underlies intestinal aging caused by mitochondrial DNA mutations. Nature Communications, 15: 546.

10.Hao, Z., Wu, Y., Huang, Y., …Liu, X*. (2025). Microprotein PLUM encoded by Lin28b uORF is a cytoplasmic determinant of pluripotency and embryonic development. Nature Communications, 16(1):10324. 

11.Bao, F., Zhou, L., Zhou, R., …Tian, M*&Liu, X*. (2022). Mitolysosome exocytosis, a mitophagy-independent mitochondrial quality control in flunarizine-induced parkinsonism-like symptoms. Science Advances, 8(15):eabk2376.

12.Wu, Y., Chen, K., Xing, G., …Liu, X*. (2019). Phospholipid remodeling is critical for stem cell pluripotency via facilitating mesenchymal-to-epithelial transition. Science Advances, 5(11):eaax7525.

13.Guo, J., Duan, L., He, X., …Liu, X*. (2021). A combined model of human iPSC-derived liver organoids and hepatocytes reveals ferroptosis in DGUOK mutant mtDNA depletion syndrome. Advanced Science 8(10):2004680. (封面)

14.Li, S., Guo, J., Ying, Z., ... Liu, X*. (2015). Valproic acid‐induced hepatotoxicity in Alpers syndrome is associated with mitochondrial permeability transition pore opening‐dependent apoptotic sensitivity in an induced pluripotent stem cell model. Hepatology, 61(5):1730-1739. 

15.Zhou, L., Bao, F., Zheng, J…Chen, G*&Liu, X*. (2025). Glucose restriction induces degeneration of neurons with mitochondrial DNA depletion by altering ER-mitochondria calcium transfer. Molecular Psychiatry 30(10):4749-4763.

16.Chen, K., Long, Q., Xing, G., …Pei, D*& Liu, X*. (2020). Heterochromatin loosening by the Oct4 linker region facilitates Klf4 binding and iPSC reprogramming. EMBO Journal, 39(1):e99165 (F1000推荐)

17.Liao, R., Wu, Y., Le, Q., … Liu, X* & Li, P*. (2023). BCL11B and the NuRD complex cooperatively guard T-cell fate and inhibit OPA1-mediated mitochondrial fusion in T cells. EMBO Journal, 42(21):e113448.

18.Xiang, G., Yang, L., Long, Q., …Liu, X*. (2017). BNIP3L-dependent mitophagy accounts for mitochondrial clearance during 3 factors-induced somatic cell reprogramming. Autophagy, 13(9):1543-1555.

19.Zhou, Y., Long, Q., Wu, H., …Liu, X*. (2020). Topology-dependent, bifurcated mitochondrial quality control under starvation. Autophagy, 16(3):562-574. (封面)

20.Wu, Y.*, Liu, Y., Huang, Y., …Liu, X*. (2026). Post-transcriptional control of endogenous retroviruses by L1td1 suppresses totipotency acquisition in pluripotent stem cells, Cell Discovery, 12(1):7.

21.Wu, Y., Chen, K., Li L., …Liu, X*. (2022). Plin2-mediated lipid droplet mobilization accelerates exit from pluripotency by lipidomic remodeling and histone acetylation. Cell Death & Differentiation, 29(11):2316-2331. (CDDpress: Readers’ Choice)

22.Xing, G., Liu, Z., Huang L., …Pei, D* Liu, X* & Chen, K*. (2022). MAP2K6 remodels chromatin and facilitates reprogramming by activating Gatad2b-phosphorylation dependent heterochromatin loosening. Cell Death & Differentiation, 29(5):1042-1054.

23.Lin, Y., Li, B.,…Liu, X*, Yan, C*, Ji, K*. (2025). Lactate-driven  histone lactylation enhances GDF15 secretion in skeletal muscle under mtDNA mutation-induced mitochondrial stress. Science Bulletin 71(5):998-1002.

24.Xing, G.,  Huang Y., Liu, W…Dong, M*, Liang, W*,  Liu, X*, Chen K*. (2026) MAP2K6 directly phosphorylates Bcl2l13 to mediate mitophagy for suppressing tumorigenicity. Cell Reports, Mar 24;45(4):117177. doi: 10.1016/j.celrep.2026.117177. (Lead Contact)

25.Yao, D., Li, Y., Zeng, S., …Liu, X*. (2022). Short-form OPA1 is a molecular chaperon in mitochondrial intermembrane space. Science China-Life Sciences, 65(2):227-235. (封面).

26.Wang, R., Bao, F., Lu, M., …Zhang, Q.*, Liu, X*. (2024). MSC-mediated mitochondrial transfer restores mitochondrial DNA and function in neural progenitor cells of Leber's Hereditary Optic Neuropathy. Science China-Life Sciences, 67(11):2511-2519.

27.Wu, H., Li, W., Zhou Y., …Liu, X*, Long, Q*. (2026) A new role of Iridium(III) Complexes in regulating pluripotency acquisition via mitochondrial remodulation. Science China-Life Sciences, 2026. Apr 3 online, https://doi.org/10.1007/s11427-025-3300-x. (封面).

28.Bao, F., Shi, H., Gao, M.,…Liu, X*. (2018). Polybrene induces neural degeneration by bidirectional Ca2+ influx dependent mitochondrial and ER-mitochondrial dynamics. Cell Death & Disease, 9(10):966.

29.Li, L., Chen, K., Wu Y.,...Liu, X*. (2017). Gadd45a opens up the promoter regions of miR-295 facilitating pluripotency induction. Cell Death & Disease, 8(10):e3107. 

30.Lin, Y., Xiao, M., Chen, H., Meng, Y., Zhao, N., Yang, L., Tang, H., Wang, J., Liu, X*, Zhu, Y.*, Zhuang, S.*. (2019). A novel mitochondrial micropeptide MPM enhances mitochondrial respiratory activity and promotes myogenic differentiation. Cell Death & Disease, 10(7):528.

31.Yang, L., Long, Q., Liu, J., ... Liu, X*. (2015). Mitochondrial fusion provides an ‘initial metabolic complementation’ controlled by mtDNA. Cellular and Molecular Life Sciences, 72(13):2585-2598. 

32.Yang, L., Lin, X., Tang, H.,....Liu, X*. (2020).  Mitochondrial DNA mutation exacerbates female reproductive aging via impairment of the NADH/NAD+ redox. Aging Cell 19(9):e13206.

33.Chen, K., Long, Q., Wang, T., … Liu, X* & Pei, D*. (2016). Gadd45a is a heterochromatin relaxer that enhances iPS cell generation. EMBO Reports,17(11): 1641-1656.

34.Liu, X., Wang, D., Jia, L.,…Liu, X* & Liang, X*. (2026).Autologous bone marrow mesenchymal stem cell mitochondrial transplantation in recurrent assisted reproductive technology failure: a randomized controlled trial. Stem Cell Research & Therapy, 2026 May 13. doi: 10.1186/s13287-026-05059-5.

35.Xiang, G., Liu, Z., Yuan, Z…. Liu, X* (2025). Perinuclear mitochondrial clustering for mesenchymal-to-epithelial transition in pluripotency induction. Stem Cell Reports 20(5):102474.

36.Bao, F., Shi, H., Long, Q., …Liu, X*. (2016). Mitochondrial membrane potential-dependent endoplasmic reticulum fragmentation is an important step in neuritic degeneration. CNS Neuroscience & Therapeutics, 22(8):648-660.  (封面)

37.Yang, L., Tang, H., Lin, X....Liu, X*. (2020). OPA1-Exon4b binds to mtDNA D-loop for transcriptional and metabolic modulation, independent of mitochondrial fusion. Frontiers in Cell and Developmental Biology, 8: 180.

38.Wu, Y., Chen, K., Liu, X., ... Liu, X*. (2015). Srebp‐1 Interacts with c‐Myc to Enhance Somatic Cell Reprogramming. Stem Cells, 34(1): 83-92.

39.Long, Q., Zhao, D., Fan, W., ... Wang X* & Liu, X*. (2015). Modeling of mitochondrial donut formation. Biophysical Journal, 109(5):892-899.

40.Liu, W., Long, Q., Chen, K., ... Liu, X*. (2013). Mitochondrial metabolism transition cooperates with nuclear reprogramming during induced pluripotent stem cell generation. Biochemical and Biophysical Research Communications, 431(4), 767-771.

41.Wu, Y., Liu, Y., Hao, Z., Liu, X*. (2022). NAD+ is critical for maintaining acetyl-CoA and H3K27ac in embryonic stem cells by Sirt1-dependent deacetylation of AceCS1. Life Medicine, 1(3), 401-405. (Most Picked Paper Award)

42.Tang, H., Hu, Z., Yang, L., ... Liu, X*. (2022). OPA1-Exon4b modulates the migration and invasion of hepatocellular carcinoma cells by ATP regulation. Mitochondrial Communications, 1, 16-22

43.Qi, J., Long, Q., Yuan Y.,…&Liu, X*. (2023). Mitochondrial DNA mutation affects the pluripotency of embryonic stem cells through modulating metabolism, Genome Instability & Disease, 4(1), 12–20.

44.Liu, X., Weaver, D., Shirihai, O., & Hajnóczky, G. (2009). Mitochondrial ‘kiss‐and‐run’: interplay between mitochondrial motility and fusion–fission dynamics. The EMBO Journal, 28(20), 3074-3089. (F1000推荐)

45.Liu, X., & Hajnoczky, G. (2011). Altered fusion dynamics underlie unique morphological changes in mitochondria during hypoxia–reoxygenation stress. Cell Death & Differentiation, 18(10), 1561-1572. (F1000推荐)

46.Weaver, D., Eisner, V., Liu, X., … & Hajnóczky, G. (2014). Distribution and apoptotic function of outer membrane proteins depend on mitochondrial fusion. Molecular Cell, 54(5), 870-878. (co-first author)