| Kdm2b Regulates Somatic Reprogramming through Variant PRC1 Complex-Dependent Function |
Zhiwei Zhou,Xuejie Yang,Jiangping He,Jing Liu,Fang Wu,Shengyong Yu,Yuting Liu,Runxia Lin,He Liu,Yuanbin Cui,Chunhua Zhou,Xiaoshan Wang,Jian Wu,Shangtao Cao,Lin Guo,Lihui Lin,Tao Wang,Xiaozhong Peng,Boqing Qiang,Andrew P.Hutchins,Duanqing Pei,Jiekai Chen |
2017 Nov; |
Cell Reports |
| Palladium-Catalyzed Imidoylative Cyclization of Tryptophan-Derived Isocyanides: Access to β-Carbolines |
Shi Tang,Jian Wang,Zhuang Xiong,Zeqiang Xie,Dengke Li,Jinbo Huang,Qiang Zhu |
2017 Oct; |
Organic Letters |
| Total Synthesis of (+)-Aplykurodinone-1 |
Bo Xu,Wen Xun,Tingzhong Wang,Fayang G. Qiu |
2017 Sep; |
Organic Letters |
| Passive DNA demethylation preferentially up-regulates pluripotency-related genes and facilitates the generation of induced pluripotent stem cells |
Songwei He, Hao Sun, Lilong Lin, Yixin Zhang, Jinlong Chen, Lining Liang, Yuan Li,Mengdan Zhang, Xiao Yang, Xiaoshan Wang, Fuhui Wang, Feiyan Zhu, Jiekai Chen,Duanqing Pei,Hui Zheng |
2017 Nov; |
Journal of Biological Chemistry |
| Gadd45a opens up the promoter regions of miR-295 facilitating pluripotency induction |
Linpeng Li,Keshi Chen,Yi Wu,Qi Long,Danyun Zhao1,Bochao Ma,Duanqing Pei,Xingguo Liu |
2017 Oct; |
Cell Death and Disease |
| Editorial overview: Cell reprogramming: Carpe diem |
Miguel A Esteban,Jianlong Wang |
2017 Oct; |
Current Opinion in Genetics & Development |
| High-affinity human PD-L1 variants attenuate the suppression of T cell activation |
Zhaoduan Liang, Ye Tian, Wenxuan Cai, Zhiming Weng, Yanyan Li, Huanling Zhang, Yifeng Bao,Yi Li |
2017 Oct; |
Oncotarget |
| Cre-dependent Cas9-expressing pigs enable efficient in vivo genome editing |
Kepin Wang, Qin Jin, Degong Ruan, Yi Yang, Qishuai Liu, Han Wu, Zhiwei Zhou, Zhen Ouyang, Zhaoming Liu, Yu Zhao, Bentian Zhao, Quanjun Zhang, Jiangyun Peng, Chengdan Lai, Nana Fan, Yanhui Liang, Ting Lan, Nan Li, Xiaoshan Wang, Xinlu Wang, Yong Fan, Pieter A. Doevendans, Joost P.G. Sluijter, Pentao Liu, Xiaoping Li,Liangxue La |
2017 Dec; |
Genome Research |
| Palladium-catalyzed C(sp(2))-H aminoimidoylation of isocyano-containing arenes: synthesis of amino substituted N-heterocycles |
Zhuang Xiong,Jian Wang,Yanbo Wang,Shuang Luo,Qiang Zhu |
2017 Sep; |
Organic Chemistry Frontiers |
| SNX16 Regulates the Recycling of E-Cadherin through a Unique Mechanism of Coordinated Membrane and Cargo Binding |
Jinxin Xu, Leilei Zhang, Yinghua Ye,Yongli Shan,Chanjuan Wan,Junfeng Wang,Duanqing Pei, Xiaodong Shu,Jinsong Liu |
2017 Aug; |
Structure |
| Chemical reprogramming of mouse embryonic and adult fibroblast into endoderm lineage |
Shangtao Cao,Shengyong Yu,Yan Chen,Xiaoshan Wang,Chunhua Zhou,Yuting Liu,Junqi Kuang,He Liu,Dongwei Li,Jing Ye,Yue Qin,Shilong Chu,Linlin Wu,Lin Guo,Yinxiong Li,Xiaodong Shu,Jiekai Chen, Jing Liu，Duanqing Pei |
2017 Nov; |
Journal of Biological Chemistry |
| Mutation of the Sp1 binding site in the 5' flanking region of SRY causes sex reversal in rabbits |
Yuning Song, Tingjun Liu, Yong Wang, Jichao Deng, Mao Chen, Lin Yuan, Yi Lu, Yuxin Xu, Haobin Yao, Zhanjun Li,Liangxue Lai |
2017 Jun; |
Oncotarget |
| BNIP3L-dependent mitophagy accounts for mitochondrial clearance during 3 factors-induced somatic cell reprogramming |
Ge Xiang, Yang Liang, Qi Long, Keshi Chen, Haite Tang, Yi Wu, Zihuang Liu, Yanshuang Zhou, Juntao Q, Lingjun Zheng, Wenbo Liu , Zhongfu Ying, Weimin Fan, Hongyan Shi, Hongmei Li, Xiaobing Lin, Mi Gao, Jinglei Liu, Feixiang Bao, Linpeng Li, Lifan Duan, Min Li,Xingguo Liu |
2017 Sep; |
Autophagy |
| Human Embryo Editing: Opportunities and Importance of Transnational Cooperation |
Duanqing Pei,David W. Beier,Ephrat Levy-Lahad,Gary Marchant,Janet Rossant,Juan Carlos Izpisua Belmonte,Robin Lovell-Badge,Rudolf Jaenisch,Alta Charo,David Baltimore |
2017 Oct; |
Cell Stem Cell |
| Models of global gene expression define major domains of cell type and tissue identity |
Andrew P. Hutchins, Zhongzhou Yang, Yuhao Li, Fangfang He, Xiuling Fu,Xiaoshan Wang, Dongwei Li, Kairong Liu, Jiangping He, Yong Wang, Jiekai Chen,Miguel A. Esteban,Duanqing Pei |
2017 Mar; |
Nucleic Acids Research |
| PRC2 specifies ectoderm lineages and maintains pluripotency in primed but not naive ESCs |
Yongli Shan, Zechuan Liang, Qi Xing, Tian Zhang, Bo Wang, Shulan Tian, Wenhao Huang, Yanqi Zhang, Jiao Yao, Yanling Zhu, Ke Huang, Yujian Liu, Xiaoshan Wang, Qianyu Chen, Jian Zhang, Bizhi Shang, Shengbiao Li, Xi Shi, Baojian Liao, Cong Zhang, Keyu Lai, Xiaofen Zhong, Xiaodong Shu, Jinyong Wang, Hongjie Yao, Jiekai Chen, Duanqing Pei, Guangjin Pan |
2017 Sep; |
Nature Communications |
| A sequential EMT-MET mechanism drives the differentiation of human embryonic stem cells towards hepatocytes |
Qiuhong Li, Andrew P. Hutchins, Yong Chen, Shengbiao Li, Yongli Shan, Baojian Liao, Dejin Zheng,Xi Shi, Yinxiong Li, Wai-Yee Chan, Guangjin Pan, Shicheng Wei, Xiaodong Shu, Duanqing Pei |
2017 May; |
Nature Communications |
| Generation of Hoxc13 knockout pigs recapitulates human ectodermal dysplasia-9 |
Kai Han, Liuping Liang, Li Li, Zhen Ouyang, Bentian Zhao, Qi Wang,Zhaoming Liu, Yu Zhao, Xiaoshuai Ren, Fei Jiang, Chengdan Lai,Kepin Wang, Sen Yan, Liang Huang, Lin Guo, Kang Zeng,Liangxue Lai,Nana Fan |
2017 Jan; |
Human Molecular Genetics |
| Fumarylacetoacetate Hydrolase Knock-out Rabbit Model for Hereditary Tyrosinemia Type 1 |
Li Li, Quanjun Zhang, Huaqiang Yang, Qingjian Zou, Chengdan Lai, Fei Jiang, Ping Zhaoa,Zhiwei Luo, Jiayin Yang, Qian Chen, Yan Wang, Philip N. Newsome, Jon Frampton, Patrick H. Maxwell,Wenjuan Lia, Shuhan Chen, Dongye Wang, Tak-Shing Siu, Sidney Tam, Hung-Fat Tse,Baoming Qin, Xichen Baoa, Miguel A. Esteban, Liangxue Lai |
2017 Mar; |
Journal of Biological Chemistry |
| Generation of Human Liver Chimeric Mice with Hepatocytes from Familial Hypercholesterolemia Induced Pluripotent Stem Cells |
Jiayin Yang, Yu Wang, Ting Zhou, Lai-Yung Wong, Xiao-Yu Tian, Xueyu Hong, Wing-Hon Lai, Ka-Wing Au, Rui Wei, Yuqing Liu, Lai-Hung Cheng, Guichan Liang, Zhijian Huang, Wenxia Fan, Ping Zhao, Xiwei Wang, David P. Iba？ez, Zhiwei Luo, Yingying Li, Xiaofen Zhong, Shuhan Chen, Dongye Wang, Li Li, Liangxue Lai, Baoming Qin, Xichen Bao, Andrew P. Hutchins, Chung-Wah Siu, Yu Huang, Esteban MA,Hung-Fat Tse |
2017 Mar; |
Stem Cell Reports |
| AXL is not essential for Zika virus infection in the mouse brain |
Feng Li,Pei-Rong Wang,Lin-Bing Qu,Chang-Hua Yi,Fu-Chun Zhang,Xiao-Ping Tang,Li-Guo Zhang,Ling Chen |
2017 Mar; |
Emerging Microbes & Infections |
| Seroprevalence of neutralizing antibodies against adenovirus type 14 and 55 in healthy adults in Southern China |
Xuehua Zheng,, Xia Rong, Ying Feng, Xikui Sun, Liang Li, Qian Wang, Min Wang, Wenkuan Liu, Chufang Li, Yiyu Yang, Rong Zhou, Jiahai Lu, Liqiang Feng,Ling Chen |
2017 Jun; |
Emerging Microbes & Infections |
| Plasmodium parasite as an effective hepatocellular carcinoma antigen glypican-3 delivery vector |
Quan Liu, Yijun Yang, Xuefang Tan, Zhu Tao, Dickson Adah, Songlin Yu, Junnan Lu, Siting Zhao, Limei Qin, Li Qin, Xiaoping Chen |
2017 Apr; |
Oncotarget |
| Copper-catalyzed regioselective 1,2-thioamidation of alkenes |
Dengke Li,Tingting Mao, Jinbo Huang,Qiang Zhu |
2017 Mar; |
Chemical Communications |
| A one-pot synthesis of [1,2,3]triazolo[1,5-a]quinoxalines from 1-azido-2-isocyanoarenes with high bond-forming efficiency |
Dengke Li, Tingting Mao, Jinbo Huang,Qiang Zhu |
2017 Jan; |
Chemical Communications |
| Palladium-Catalyzed Enantioselective C(sp(2))-H lmidoylation by Desymmetrization |
Jian Wang,De-Wei Gao,Jinbo Huang,Shi Tang,Zhuang Xiong,Huaanzi Hu,Shu-Li You,Qiang Zhu |
2017 Jun; |
ACS Catalysis |
| Denitrogenative Imidoyl Radical Cyclization: Synthesis of 2-Substituted Benzoimidazoles from 1-Azido-2-isocyanoarenes. |
Dengke Li, Tingting Mao, Jinbo Huang,Qiang Zhu |
2017 Jun; |
Organic Letters |
| RNA Helicase DDX5 Inhibits Reprogramming to Pluripotency by miRNA-Based Repression of RYBP and its PRC1-Dependent and -Independent Functions |
Huanhuan Li, Ping Lai, Jinping Jia, Yawei Song, Qing Xia, Kaimeng Huang, Na He, Wangfang Ping, Jiayu Chen, Zhongzhou Yang, Jiao Li, Mingze Yao, Xiaotao Dong, Jicheng Zhao, Chunhui Hou, Miguel A. Esteban, Shaorong Gao, Duanqing Pei, Andrew P. Hutchins,Hongjie Yao |
2017 Apr; |
Cell Stem Cell |
| Pentafluorosulfanyl-Substituted Benzopyran Analogues As New Cyclooxygenase-2 Inhibitors with Excellent Pharmacokinetics and Efficacy in Blocking Inflammation |
Yanmei Zhang,Yican Wang,Chuang He,Xiaorong Liu,Yongzhi Lu,Tingting Chen,Qiong Pan,Jingfang Xiong,Miaoqin She,Zhengchao Tu,Xiaochu Qin, Minke Li,Micky D. Tortorella,John J.Talley |
2017 May; |
Journal of Medicinal Chemistry |
| Molecular basis for the genome engagement by Sox proteins |
Linlin Hou, Yogesh Srivastava, Ralf Jauch |
2017 Mar; |
Seminars in Cell & Developmental Biology |
