| Changing POU dimerization preferences converts Oct6 into a pluripotency inducer |
Stepan Jerabek, Calista KL Ng, Guangming Wu, Marcos J Arauzo-Bravo, Kee-Pyo Kim,Daniel Esch, Vikas Malik, Yanpu Chen, Sergiy Velychko, Caitlin M MacCarthy,Xiaoxiao Yang, Vlad Cojocaru, Hans R Sch？ler,Ralf Jauch |
2017 Feb; |
EMBO Reports |
| Suppressing P16Ink4a and P14ARF pathways overcomes apoptosis in individualized human embryonic stem cells |
Wenqian Wang, Yanling Zhu, Ke Huang, Yongli Shan, Juan Du, Xiaoya Dong, Ping Ma, Pengfei Wu, Jian Zhang, Wenhao Huang, Tian Zhang, Baojian Liao, Deyang Yao, Guangjin Pan,Jiajun Liu |
2017 Mar; |
FASEB Journal |
| Brown Adipogenic Reprogramming Induced by a Small Molecule |
Nie Baoming，Nie Tao，Hui Xiaoyan，Gu Ping，Mao Liufeng，Li Kuai，Yuan Ran，Zheng Jiashun，Wang Haixia，Li Ke，Tang Shibing，Zhang Yu，Xu Tao，Xu Aimin，Wu Donghai，Ding Shen |
2017 Jan; |
Cell Reports |
| Visualization and Quantification of Browning Using a Ucp1-2A-Luciferase Knock-in Mouse Model |
Mao Liufeng，Nie Baoming，Nie Tao，Hui Xiaoyan，Gao Xuefei，Lin Xiaoliang，Liu Xin，Xu Yong，Tang Xiaofeng，Yuan Ran，Li Kuai，Li Peng，Ding Ke，Wang Yu，Xu Aimin，Fei Jian，Han Weiping，Liu Pentao，Madsen Lise，Kristiansen Karsten，Zhou Zhiguang，Ding Sheng，Wu Donghai |
2017 Feb; |
Diabetes |
| Current status and perspectives of patient-derived xenograft models in cancer research |
Yunxin Lai, Xinru Wei, Shouheng Lin, Le Qin, Lin Cheng,Peng Li |
2017 May; |
Journal of Hematology & Oncology |
| Anti-GPC3-CAR T Cells Suppress the Growth of Tumor Cells in Patient-Derived Xenografts of Hepatocellular Carcinoma |
Zhiwu Jiang, Xiaofeng Jiang, Suimin Chen, Yunxin Lai, Xinru Wei,Baiheng Li, Simiao Lin, Suna Wang, Qiting Wu, Qiubin Liang, Qifa Liu,Muyun Peng, Fenglei Yu, Jianyu Weng, Xin Du, Duanqing Pei, Pentao Liu,Yao Yao, Ping Xue,Peng Li |
2017 Jan; |
Frontiers In Immunology |
| Incorporation of a hinge domain improves the expansion of chimeric antigen receptor T cells |
Le Qin, Yunxin Lai, Ruocong Zhao, Xinru Wei, Jianyu Weng, Peilong Lai, Baiheng Li,Simiao Lin, Suna Wang, Qiting Wu, Qiubin Liang, Yangqiu Li, Xuchao Zhang, Yilong Wu, Pentao Liu,Yao Yao, Duanqing Pei, Xin Du，Peng Li |
2017 Mar; |
Journal of Hematology & Oncology |
| PSCA and MUC1 in non-small-cell lung cancer as targets of chimeric antigen receptor T cells |
Xinru Wei, Yunxin Lai, Jin Li, Le Qin, Youdi Xu, Ruocong Zhao, Baiheng Li,Simiao Lin, Suna Wang, Qiting Wu, Qiubin Liang, Muyun Peng, Fenglei Yu,Yangqiu Li, Xuchao Zhang, Yilong Wu, Pentao Liu, Duanqing Pei, Yao Yao，Peng Li |
2017 Feb |
OncoImmunology |
| Organocatalytic Friedel-Crafts Alkylation/Lactonization Reaction of Naphthols with 3-Trifluoroethylidene Oxindoles: The Asymmetric Synthesis of Dihydrocoumarins |
Yun-Long Zhao, Qin-Xin Lou, Long-Sheng Wang, Wen-Hui Hu,Jun-Ling Zhao |
2017 Jan |
Angewandte Chemie-International Edition |
| Portable and quantitative monitoring of mercury ions using DNA-gated mesoporous silica nanoparticles using a glucometer readout |
Xiaoling Liang, Lin Wang, Dou Wang, Lingwen Zeng,Zhiyuan Fang |
2016 Feb |
Chemical Communications |
| Harmine Induces Adipocyte Thermogenesis through RAC1-MEK-ERK-CHD4 Axis |
Tao Nie, Xiaoyan Hui, Liufeng Mao, Baoming Nie, Kuai Li, Wei Sun, Xuefei Gao,Xiaofeng Tang, Yong Xu, Baishan Jiang, Zhengcao Tu, Peng Li, Ke Ding, Weiping Han,Shaoping Zhang, Aimin Xu, Sheng Ding, Pentao Liu, Adam Patterson, Garth Cooper,Donghai Wu |
2016 Nov |
Scientific Reports |
| Low dose triptolide reverses chemoresistance in adult acute lymphoblastic leukemia cells via reactive oxygen species generation and DNA damage response disruption |
Zhao H, Shi P, Deng M, Jiang Z, Li Y, Kannappan V, Wang W, Peng Li, Xu B |
2016 Dec |
Oncotarget |
| Heterogeneity of CD34 and CD38 expression in adult acute B lymphoblastic leukemia cells is reversible and not hierarchically organized |
Zhiwu Jiang,Manman Deng,Xinru Wei,Wei Ye,Yiren Xiao,Simiao Lin,Suna Wang,Baiheng Li,Xin Liu,Gong Zhang,Peilong Lai,Jianyu Weng,Donghai Wu, Haijia Chen, Wei Wei, Yuguo Ma, Yangqiu Li, Pentao Liu, Xin Du, Duanqing Pei, Yao Yao, Bing Xu,Peng Li |
2016 Sep |
Journal of Hematology & Oncology |
| GZD824 suppresses the growth of human B cell precursor acute lymphoblastic leukemia cells by inhibiting the SRC kinase and PI3K/AKT pathways |
Wei Ye, Zhiwu Jiang, Xiaoyun Lu, Xiaomei Ren, Manman Deng, Shouheng Lin, Yiren Xiao, Simiao Lin, Suna Wang, Baiheng Li, Yi Zheng, Peilong Lai, Jianyu Weng, Donghai Wu, Yuguo Ma, Xudong Chen, Zhesheng Wen, Yaoyu Chen, Xiaoyan Feng, Yangqiu Li, Pentao Liu, Xin Du, Duanqing Pei, Yao Yao, Bing Xu, Ke Ding, Peng Li |
2016 Jul |
Oncotarget |
| Structure and decoy-mediated inhibition of the SOX18/Prox1-DNA interaction.Nucleic Acids Research |
Miriam Klaus, Nina Prokoph, Mathias Girbig, Xuecong Wang, Yong-Heng Huang, Yogesh Srivastava, Linlin Hou, Kamesh Narasimhan,
Prasanna R. Kolatkar, Mathias Francois,Ralf Jauch |
2016 May |
Nucleic Acids Research |
| Molecular basis for the genome engagement by Sox proteins |
Linlin Hou, Yogesh Srivastava, Ralf Jauch |
2016 Aug |
Seminars in Cell & Developmental Biology |
| Quantitative profiling of selective Sox/POU pairing on hundreds of sequences in parallel by Coop-seq |
Yiming K. Chang, Yogesh Srivastava, Caizhen Hu, Adam Joyce, Xiaoxiao Yang, Zheng Zuo, James J. Havranek, Gary D. Stormo, Ralf Jauch |
2017 Jan |
Nucleic Acids Research |
| Lysine-specific histonedemethylase 1 inhibition promotes reprogramming by facilitating the expression of exogenous transcriptional factors and metabolic switch |
Hao Sun, Lining Liang1, Yuan Li, Chengqian Feng, Lingyu Li, Yixin Zhang, Songwei He,Duanqing Pei1, Yunqian Guo,Hui Zheng |
2016 Aug |
Scientific Reports |
| Intramolecular Imidoylative Heck Reaction: Synthesis of Cyclic Ketoimines from Functionalized Isocyanide |
Jian Wang, Shi Tang,Qiang Zhu |
2016 Jul |
Organic Letters |
| Identification and characterization of rabbit ROSA26 for gene knock-in and stable reporter gene expression |
Dongshan Yang, Jun Song, Jifeng Zhang, Jie Xu, Tianqing Zhu, Zhong Wang, Liangxue Lai,Y. Eugene Chen |
2016 Apr |
Scientific Reports |
| CRISPR/Cas9-mediated mutation of PHEX in rabbit recapitulates human X-linked hypophosphatemia (XLH) |
Tingting Sui1, Lin Yuan1, Huan Liu, Mao Chen, Jichao Deng, Yong Wang, Zhanjun Li, Liangxue Lai |
2016 Jul |
Human Molecular Genetics |
| CRISPR/Cas9-mediated GJA8 knockout in rabbits recapitulates human congenital cataracts |
Lin Yuan, Tingting Sui, Mao Chen, Jichao Deng, Yongye Huang, Jian Zeng, Qingyan Lv, Yuning Song, Zhanjun Li,Liangxue Lai |
2016 Feb |
Scientific Reports |
| Efficient Generation of Myostatin Gene Mutated Rabbit by CRISPR/Cas9 |
Qingyan Lv, Lin Yuan, Jichao Deng, Mao Chen, Yong Wang, Jian Zeng, Zhanjun Li,Liangxue Lai |
2016 Apr |
Scientific RepoRts |
| Conversion of embryonic stem cells into extraembryonic lineages by CRISPR-mediated activators |
Shu Wei, Qingjian Zou, Sisi Lai, Quanjun Zhang, Li Li, Quanmei Yan,Xiaoqing Zhou, Huilin Zhong， Liangxue Lai |
2016 Jan |
Scientific Reports |
| Genetically humanized pigs exclusively expressing human insulin are generated through custom endonuclease-mediated seamless engineering |
Yi Yang, Kepin Wang, Han Wu, Qin Jin, Degong Ruan, Zhen Ouyang, Bentian Zhao, Zhaoming Liu, Yu Zhao, Quanjun Zhang, Nana Fan, Qishuai Liu, Shimei Guo，Lei Bu, Yong Fan, Xiaofang Sun, Xiaoping Li, Liangxue Lai |
2016 Apr |
Journal of Molecular Cell Biology |
| Structure-Based Design of Potent Nicotinamide Phosphoribosyltransferase Inhibitors with Promising in Vitro and in Vivo Antitumor Activities |
Jinhong Bai, Chenzhong Liao,Yanghan Liu, Xiaochu Qin, Jiaxuan Chen, Yatao Qiu,Dongguang Qin, Zheng Li,Zheng-Chao Tu,Sheng Jiang |
2016 Jun |
Journal of Medicinal Chemistry |
| Pd-Catalyzed C(sp2)-H carbonylation of 2-benzylpyridines for the synthesis of pyridoisoquinolinones |
Zeqiang Xie, Shuang Luo,Qiang Zhu |
2016 Oct |
Chemical Communications |
| A metal-free synthesis of 2-aminobenzothiazoles through aminyl radical addition to aryl isothiocyanates |
Yimiao He, Jing Li, Shuang Luo, Jinbo Huang,Qiang Zhu |
2016 Jun |
Chemical Communications |
| Transcriptional Control of Somatic Cell Reprogramming |
Yan Xu, Meng Zhang, Wenjuan Li, Xihua Zhu, Xichen Bao, Baoming Qin, Andrew P. Hutchins, Miguel A. Esteban |
2016 Apr |
Trends in Cell Biology |
| Gadd45a is a heterochromatin relaxer that enhances iPS cell generation |
Keshi Chen, Qi Long, Tao Wang, Danyun Zhao, Yanshuang Zhou, Juntao Qi, Yi Wu, Shengbiao Li, Chunlan Chen, Xiaoming Zeng, Jianguo Yang, Zisong Zhou, Weiwen Qin, Xiyin Liu, Yuxing Li, Yingying Li, Xiaofen Huang, Dajiang Qin, Jiekai Chen, Guangjin Pan, Hans R Sch？ler, Guoliang Xu, Xingguo Liu, Duanqing Pei |
2016 Nov |
EMBO Reports |
