| Design, Synthesis, and Biological Evaluation of 1-(Indolizin-3-yl)ethan-1-ones as CBP Bromodomain Inhibitors for the Treatment of Prostate Cancer |
Qiuping Xiang, Chao Wang, Tianbang Wu, Cheng Zhang, Qingqing Hu, Guolong Luo, Jiankang Hu , Xiaoxi Zhuang, Lingjiao Zou , Hui Shen, Xishan Wu , Yan Zhang , Xiangqian Kong, Jinsong Liu, Yong Xu |
2022 |
Journal of Medicinal Chemistry |
| Shared IGHV1-69-encoded neutralizing antibodies contribute to the emergence of L452R substitution in SARS-CoV-2 variants |
Qihong Yan , Ruitian Hou , Xiaohan Huang , Yanjun Zhang , Ping He , Yudi Zhang , Banghui Liu , Qian Wang , Haiyue Rao , Xianying Chen , Xinwei Zhao , Xuefeng Niu , Jincun Zhao , Xiaoli Xiong , Ling Chen |
2022 |
Emerging Microbes & Infections |
| Origin and Reversion of Omicron Core Mutations in the Evolution of SARS-CoV-2 Genomes |
Xin-Wei Zhao, Luyao Qin, Xiao Ding, Yudi Zhang, Xuefeng Niu, Feng Gao , Taijiao Jiang
and Ling Chen. |
2022 |
Viruses |
| Discovery, optimization and evaluation of 1-(indolin-1-yl)ethan-1- ones as novel selective TRIM24/BRPF1 bromodomain inhibitors |
Qiuping Xiang,Guolong Luo,Cheng Zhang,Qingqing Hua,Chao Wang,Tianbang Wu,c,Hongrui Xu,Jiankan gHu,Xiaoxi Zhuang,Maofeng Zhang,Shuang Wu,Jinxin Xu,YanZhang,Jinsong Liu,Yong Xu |
2022 |
European Journal of Medicinal Chemistry |
| Nuclear localization of mitochondrial TCA cycle enzymes modulates pluripotency via histone acetylation |
Wei Li, Qi Long , Hao Wu, Yanshuang Zhou , Lifan Duan, Hao Yuan , Yingzhe Ding , Yile Huang , Yi Wu , Jinyu Huang, Delong Liu, Baodan Chen, Jian Zhang , Juntao Qi, Shiwei Du, Linpeng Li , Yang Liu, Zifeng Ruan, Zihuang Liu, Zichao Liu, Yifan Zhao , Jianghuan Lu, Junwei Wang, Wai-Yee Chan & Xingguo Liu. |
2022 |
Nature Communications |
| Integrative analysis reveals structural basis for transcription activation of Nurr1 and Nurr1-RXRα heterodimer |
Mohan Zhao,Na Wang,Yaoting Guo,Jingwen Li,Yue Yin,Yan Dong,Jiabin Zhu,Chao Peng,Tingting Xu,Jinsong Liu |
2022 |
Proceedings of the National Academy of Sciences of the United States of America |
| YY1 safeguard multidimensional epigenetic landscape associated with extended pluripotency |
Xiaotao Dong,？Rong Guo,？Tianrong Ji,？Jie Zhang,？Jun Xu,？Yaoyi Li,？Yingliang Sheng,？Yuxiang Wang,？Ke Fang,？Yulin Wen,？Bei Liu,？Gongcheng Hu,？Hongkui Deng,？Hongjie Yao |
2022 |
Nucleic Acids Research |
| Identification of a group of bisbenzylisoquinoline (BBIQ) compounds as ferroptosis inhibitors |
Yipu Fan, Yihan Zhang, Kunyu Shi, Shan Cheng, Duanqing Pei and Xiaodong Shu |
2022 |
Cell Death＆Disease |
| From immune equilibrium to immunodynamics |
Xiaoping Chen |
2022 |
Frontiers in Microbiology |
| Parallel Kinetic Resolution through Palladium-Catalyzed Enantioselective Cycloimidoylation: En Route to Divergent N-Heterocycles Bearing a Quaternary Stereogenic Center |
Xilong Wang, Yu Luo, Jing Li, Chaoqin Wang, Qianwen Liu, Yimiao He, Shuang Luo* and Qiang Zhu |
2022 |
ACS Catalysis |
| Hepatic DKK1-driven steatosis is CD36 dependent |
Zhen Yang？,？Xinping Huang,？Jiaye Zhang,？Kai You,？Yue Xiong,？Ji Fang,？Anteneh Getachew,？Ziqi Cheng,？Xiaorui Yu,？Yan Wang,？Feima Wu,？Ning Wang,？Shufen Feng,？Xianhua Lin,？Fan Yang,？Yan Chen,？Hongcheng Wei,？Yin-Xiong Li |
2022 |
LIFE SCIENCE ALLIANCE |
| Harnessing enhanced CRISPR/Cas12a trans-cleavage activity with
extended reporters and reductants for early diagnosis of Helicobacter pylori,
the causative agent of peptic ulcers and stomach cancer |
Jean de Dieu Habimana, Omar Mukama, Guiquan Chen, Mengjun Chen, Obed
Boadi Amissah, Lin Wang, Yujie Liu, Yirong Sun, Amy L. Li, Sihao Deng,
Jufang Huang, Xiao-xin Yan, Theobard Rutaganda, Dieudonne Mutangana, Lin-Ping Wu,
Rongqi Huang ,Zhiyuan Li |
2022 |
Biosensors and Bioelectronics |
| IReNA: integrated regulatory network analysis of single-cell transcriptomes and chromatin accessibility profiles |
Junyao Jiang,Pin Lyu,Jinlian Li,Sunan Huang,Jiawang Tao,Seth Blackshaw,Jiang Qian,and Jie Wang. |
2022 |
iScience |
| Structural Studies Reveal Unique Non-canonical Regulators of G Protein Signaling Homology (RH) Domains in Sorting Nexins |
Yulong Zhang,Rui Chen,Yan Dong,Jiabin Zhu, Kai Su,Jinsong Liu and Jinxin Xu |
2022 |
JOURNAL OF MOLECULAR BIOLOGY |
| Preclinical Study of Plasmodium Immunotherapy Combined with Radiotherapy for Solid Tumors |
Tao, Zhu, Wenting Ding, Zhipeng Cheng, Yinfang Feng, Zhongkui Kang, Runmin Qiu, Siting Zhao, Wen Hu, Fang Zhou, Donghai Wu, Ziyuan Duan, Li Qin, and Xiaoping Chen. |
2022 |
Cells |
