Estrogen-related receptor gamma regulates hepatic triglyceride metabolism through phospholipase A2 G12B |
Longhui Chen,Min Wu,Shengnan Zhang,Wenjuan Tan,Min Guan,Liqiang Feng,Chen Chen,Jun Tao,Ling Chen,Linbing Qu |
2019 Jul; |
FASEB Journal |
Detection of Novel Mutations Associated with Independent and Cross-resistance to Isoniazid and Protionamide in Mycobacterium tuberculosis Clinical Isolates |
M.M.Islam,Y.Tan,Y.Gao,H.M.A.Hameed,G.Surineni,X.Li,Z.Liu,S.Tan,……,W.W.Yew,J.Liu,N.Zhong,T.Zhang |
2019 Aug; |
Clinical Microbiology and Infection |
Mesenchymal-epithelial transition in development and reprogramming |
Duanqing Pei,Xiaodong Shu,Ama Gassama-Diagne,Jean Paul Thiery |
2019 Jan; |
Nature Cell Biology |
Induction of Pluripotent Stem Cells from Mouse Embryonic Fibroblasts by Jdp2-Jhdm1b-Mkk6-Glis1-Nanog-Essrb-Sall4 |
Bo Wang,Linlin Wu,Dongwei Li,Yuting Liu,Jing Guo,Chen Li,Yuxiang Yao,Yaofeng Wang,Guoqing Zhao,Xiaoshan Wang,Meijun Fu,He Liu,Shangtao Cao,Chuman Wu,Shengyong Yu,Chunhua Zhou,Yue Qin,Junqi Kuang,Jin Ming,Shilong Chu,Xuejie Yang,Ping Zhu,Guangjin Pan,Jiekai Chen,Jing Liu,Duanqing Pei |
2019 Jun; |
Cell Reports |
Efficient base editing for multiple genes and loci in pigs using base editors |
Jingke Xie,Weikai Ge,Nan Li,Qishuai Liu,Fangbing Chen,Xiaoyu Yang,Xingyun Huang,Zhen Ouyang,Quanjun Zhang,Yu Zhao,Zhaoming Liu,Shixue Gou,Han Wu,Chengdan Lai,Nana Fan,Qin Jin,Hui Shi,Yanhui Liang,Ting Lan,Longquan Quan,Xiaoping Li,Kepin Wang,Liangxue Lai |
2019 Jun; |
Nature Communications |
Enantioselective Synthesis of 2‐Oxindole Spirofused Lactones and Lactams by Heck/Carbonylative Cylization Sequences: Method Development and Applications |
Huaanzi Hu,Fan Teng,Jian Liu,Weiming Hu,Shuang Luo,Qiang Zhu |
2019 Jul; |
Angewandte Chemie-International Edition |
Selective C-H or N-H Imidoylative Annulation of 2-(2-Isocyanophenyl)-1H-indoles Leading to Diverse Indole-fused Scaffolds |
Fan Teng,Weiming Hu,Huaanzi Hu,Shuang Luo,Qiang Zhu |
2019 Mar; |
Advanced Synthesis & Catalysis |
Plasmodium infection inhibits the expansion and activation of MDSCs and Tregs in the tumor microenvironment in a murine Lewis lung cancer model |
Dickson Adah,Yijun Yang,Quan Liu,Kranthi Gadidasu,Zhu Tao,Songlin Yu,Linglin Dai,Xiaofen Li,Siting Zhao,Limei Qin,Li Qin,Xiaoping Chen |
2019 Apr; |
Cell Communication and Signaling |
Discovery and Characterization of XY101, a Potent, Selective, and Orally Bioavailable RORγ Inverse Agonist for Treatment of Castration-Resistant Prostate Cancer |
Yan Zhang,Xishan Wu,Xiaoqian Xue,Chenchang Li,Junjian Wang,Rui Wang,cheng Zhang,Chao Wang,Yudan Shi,Lingjiao Zou,Qiu Li,Zenghong Huang,Xiaojuan Hao,Kerry M. Loomes,Donghai Wu,Hongwu Chen,Jinxin Xu,Yong Xu |
2019 May; |
Journal of Medicinal Chemistry |
An alternative CTCF isoform antagonizes canonical CTCF occupancy and changes chromatin architecture to promote apoptosis |
Jiao Li,Kaimeng Huang,Gongcheng Hu,Isaac A. Babarinde,Yaoyi Li,Xiaotao Dong,Yu-Sheng Chen,Liping Shang,Wenjing Guo,Junwei Wang,Zhaoming Chen, Andrew P. Hutchins,Yun-Gui Yang,Hongjie Yao |
2019 Apr; |
Nature Communications |
Total Synthesis of (-)-Daphenylline |
Bo Xu,Bingyang Wang,Wen Xun,Fayang G.Qiu |
2019 Apr; |
Angewandte Chemie-International Edition |
The compound TB47 is highly bactericidal against Mycobacterium ulcerans in a Buruli ulcer mouse model |
Yang Liu,Yamin Gao,Jianxiong Liu,Yaoju Tan,Zhiyong Liu,Chiranjibi Chhotaray,Huofeng Jiang,Zhili Lu,Gift Chiwala,Shuai Wang,Gaelle Makafe, Md Mahmudul Islam,H. M. Adnan Hameed,Xingshan Cai,Changwei Wang,Xinjie Li,Shouyong Tan,Tianyu Zhang |
2019 Jan; |
Nature Communications |
Mesothelin is a target of chimeric antigen receptor T cells for treating gastric cancer |
Jiang Lv,Ruocong Zhao,Di Wu, Diwei Zheng,Zhiping Wu,Jingxuan Shi,Xinru Wei,Qiting Wu,Youguo Long,Simiao Lin,Suna Wang,Zhi Wang,Yang Li,Yantao Chen,Qing He,Suimin Chen,Huihui Yao,Zixia Liu,Zhaoyang Tang,Yao Yao,Duanqing Pei,Pentao Liu,Xuchao Zhang,Zhenfeng Zhang,Shuzhong Cui,Ren Chen,Peng Li |
2019 Feb; |
Journal of Hematology & Oncology |
High-affinity human programmed death-1 ligand-1 variant promotes redirected T cells to kill tumor cells |
Zhaoduan Liang,Yanyan Li,Ye Tiana,Huanling Zhang,Wenxuan Cai,Anan Chen,Lin Chen,Yifeng Bao,Bo Xiang,Heping Kan,Yi Li |
2019 Apr; |
Cancer Letters |
Resolving Cell Fate Decisions during Somatic Cell Reprogramming by Single-Cell RNA-Seq |
Lin Guo,Lihui Lin,Xiaoshan Wang,Mingwei Gao,hangtao Cao,Yuanbang Mai,Fang Wu,Junqi Kuang,He Liu,Jiaqi Yang,Shilong Chu,Hong Song,Dongwei Li,Yujian Liu,Kaixin Wu,Jiadong Liu,Jinyong Wang,Guangjin Pan,Andrew P.Hutchins,Jing Liu,Duanqing Pei,Jiekai Chen |
2019 Feb; |
Molecular Cell |
Transposable elements are regulated by context-specific patterns of chromatin marks in mouse embryonic stem cells |
Jiangping He, Xiuling Fu, Meng Zhang, Fangfang He, Wenjuan Li, Mazid Md. Abdul,Jianguo Zhou, Li Sun, Chen Chang, Yuhao Li, He Liu, Kaixin Wu1, Isaac A. Babarinde, Qiang Zhuang,Yuin-Han Loh, Jiekai Chen, Miguel A. Esteban,Andrew P.Hutchins |
2019 Jan; |
Nature Communications |
The Battle between TET Proteins and DNA Methylation for the Right Cell |
Dongwei Li,Jiekai Chen,Duanqing Pei |
2018 Dec; |
Trends in Cell Biology |
DNAX-activating protein 10 co-stimulation enhances the anti-tumor efficacy of chimeric antigen receptor T cells |
Ruocong Zhao,Lin Cheng,Zhiwu Jiang,Xinru Wei,Baiheng Li,Qiting Wu,Suna Wang,Simiao Lin,Youguo Long,Xuchao Zhangd,Yilong Wud,Xin Due,Duanqing Pei,Pentao Liu,Yangqiu Li,Shuzhong Cui,Yao Yao,Peng Li |
2018 Nov; |
OncoImmunology |
Polyester based nanovehicles for siRNA delivery |
Zejun Xu,Danyang Wang,Yanqin Cheng,Mingshi Yang,Lin-Ping Wu |
2018 Nov; |
Materials Science & Engineering C-Materials for Biological Applications |
Ligand binding and heterodimerization with retinoid X receptor (RXR) induce farnesoid X receptor (FXR) conformational changes affecting coactivator binding |
Na Wang,Qingan Zou,Jinxin Xu,Jiancun Zhang,Jinsong Liu |
2018 Nov; |
Journal of Biological Chemistry |
Short-Term Mitochondrial Permeability Transition Pore Opening Modulates Histone Lysine Methylation at the Early Phase of Somatic Cell Reprogramming |
Zhongfu Ying,Ge Xiang,Lingjun Zheng,Haite Tang,Lifan Duan,Xiaobing Lin,Qiuge Zhao,Keshi Chen,Yi Wu,Guangsuo Xing,Yiwang Lv,Linpeng Li,Liang Yang,Feixiang Bao,Qi Long,Yanshuang Zhou,Xueying He,Yaofeng Wang,Minghui Gao,Duanqing Pei,Wai-Yee Chan,Xingguo Liu |
2018 Dec; |
Cell Metabolism |
Polybrene induces neural degeneration by bidirectional Ca2+ influx-dependent mitochondrial and ER-mitochondrial dynamics |
Feixiang Bao,Hongyan Shi,Mi Gao,Liang Yang,Lingyan Zhou,Qiuge Zhao,Yi Wu,Keshi Chen,Ge Xiang,Qi Long,Jingyi Guo,Jian Zhang,Xingguo Liu |
2018 Sep; |
Cell Death & Disease |
BMI1 enables interspecies chimerism with human pluripotent stem cells |
Ke Huang,Yanling Zhu,Yanlin Ma,Bentian Zhao,Nana Fan,Yuhang Li,Hong Song,Shilong Chu,Zhen Ouyang,Quanjun Zhang,Qi Xing,Chengdan Lai,Nan Li, Tian Zhang,Jiaming Gu,Baoqiang Kang,Yongli Shan,Keyu Lai,Wenhao Huang,Yuchan Mai,Qing Wang,Jinbing Li,Aiping Lin,Yanqi Zhang,Xiaofen Zhong, Baojian Liao,Liangxue Lai,Jiekai Chen,Duanqinng Pei,Guangjin Pan |
2018 Nov; |
Nature Communications |
Immune Protection of SIV Challenge by PD-1 Blockade During Vaccination in Rhesus Monkeys |
Enxiang Pan,Fengling Feng,Pingchao Li,Qing Yang,Xiuchang Ma,Chunxiu Wu,Jin Zhao,Hongbin Yan,Rulei Chen, Ling Chen,Caijun Sun |
2018 Oct; |
Frontiers in Immunology |
Deficiency in class III PI3-kinase confers postnatal lethality with IBD-like features in zebrafish |
Shaoyang Zhao,Jianhong Xia,Xiuhua Wu,Leilei Zhang,Pengtao Wang,Haiyun Wang,Heying Li,Xiaoshan Wang,Yan Chen,Jean Agnetti,Yinxiong Li,Duanqing Pei,Xiaodong Shu |
2018 Jul; |
Nature Communications |
Directed evolution of reprogramming factors by cell selection and sequencing |
Veeramohan Veerapandian,Jan Ole Ackermann,Yogesh Srivastava,Vikas Malik,Mingxi Weng,Xiaoxiao Yang,Ralf Jauch |
2018 Aug; |
Stem Cell Reports |
Diversity among POU transcription factors in chromatin recognition and cell fate reprogramming |
Vikas Malik,Dennis Zimmer,Ralf Jauch |
2018 May; |
Cellular and Molecular Life Sciences |
DNA-mediated dimerization on a compact sequence signature controls enhancer engagement and regulation by FOXA1 |
Xuecong Wang,Yogesh Srivastava,Aleksander Jankowski,Vikas Malik,Yuanjie Wei, Ricardo CH del Rosario,Vlad Cojocaru, Shyam Prabhakar,Ralf Jauch |
2018 Jun; |
Nucleic Acids Research |
Engineering CRISPR/Cpf1 with tRNA promotes genome editing capability in mammalian systems |
Han Wu, Qishuai Liu,Hui Shi,Jingke Xie, Quanjun Zhang,Zhen Ouyang, Nan Li,Yi Yang, Zhaoming Liu,Yu Zhao, Chengdan Lai,Degong Ruan,Jiangyun Peng,Weikai Ge,Fang bing Chen,Nana Fan,Qin Jin,Yanhui Liang,Ting Lan, Xiaoyu Yang,Xiaoshan Wang,Zhiyong Lei,Pieter A. Doevendans,Joost P. G. Sluijter,Kepin Wang,Xiaoping Li,Liangxue Lai |
2018 Oct; |
Cellular and Molecular Life Sciences |
Copper-Catalyzed Bromodifluoroacetylation of Alkenes with Ethyl Bromodifluoroacetate |
Dengke Li,Tingting Mao,Jibo Huang,Qiang zhu |
2018 Sep; |
Journal of Organic Chemistry |