2002年-2006年：清华大学生物科学与技术系，博士

1998年-2002年：山东大学生命科学学院，学士

2007年-2010年: Thomas Jefferson University, 博士后

2010年－至今： 中国科学院广州生物医药与健康研究院 研究员

·国家自然科学“杰出青年“基金 

·国家重点研发计划首席科学家

·广东省科学技术奖自然科学一等奖（第一完成人）

·树兰医学青年奖

·丁颖科技奖

·国家自然科学优秀青年基金

·2016年干细胞青年研究员奖

·广东省自然科学杰出青年基金获得者（首届）

·国际生物物理学会"2011 Young Bioenergeticist award"

·中国科学院广州教育基地优秀研究生导师

·中国科学院广州分院优秀青年科学家

1. Hu,Z.,Yang,L.,Zhang,M.,…Liu,X*. (2024). A novel protein CYTB-187AA encoded by the mitochondrial gene CYTB modulates mammalian early development Cell Metabolism,36(7):1586-1597.e7. (Cell Metabolism当期专文评述)
2. Ying,Z.,Xiang G.,Zheng,L.,…Liu,X*. (2018). Short-term mitochondrial permeability transition pore opening modulates histone lysine methylation at the early phase of somatic cell reprogramming. Cell Metabolism,28(6):935-945.
3. Ying,Z.,Chen K.,Zheng,L.,…Liu,X*. (2016). Transient activation of mitoflashes modulates Nanog at the early phase of somatic cell reprogramming. Cell Metabolism,23(1):220-226.
4. Li,L.,Chen,K.,Wang,T.,…Liu,X*. (2020). Glis1 facilitates induction of pluripotency via an epigenome-metabolome-epigenome signaling cascade. Nature Metabolism 2(9):882-892.
5. Long,Q.,Zhou,Y.,Wu,H.,…Liu,X*. (2021). Phase separation drives the self-assembly of mitochondrial nucleoids for transcriptional modulation. Nature Structural & Molecular Biology 28(11):900-908.
6. Li,W.,Long,Q.,Wu,H.,…Liu,X*. (2022). Nuclear localization of mitochondrial TCA cycle enzymes modulates pluripotency via histone acetylation. Nature Communications, 13(1):7414. (Editors’Highlights)
7. Yang,L.,Ruan,Z.,Lin,X.,…Liu,X*. (2024). NAD⁺ dependent UPR^mt activation underlies intestinal aging caused by mitochondrial DNA mutations Nature Communications, 15: 546 
8. Bao,F.,Zhou,L.,Zhou,R.,…Tian,M*&Liu,X*. (2022). Mitolysosome exocytosis,a mitophagy-independent mitochondrial quality control in flunarizine-induced parkinsonism-like symptoms. Science Advances,8(15):eabk2376.
9. Wu,Y.,Chen,K.,Xing,G.,…Liu,X*. (2019). Phospholipid remodeling is critical for stem cell pluripotency via facilitating mesenchymal-to-epithelial transition. Science Advances,5(11):eaax7525.
10. Guo,J.,Duan,L.,He,X.,…Liu,X*. (2021). A combined model of human iPSC-derived liver organoids and hepatocytes reveals ferroptosis in DGUOK mutant mtDNA depletion syndrome. Advanced Science 8(10):2004680. (封面)
11. Li,S.,Guo,J.,Ying,Z.,...Liu,X*. (2015). Valproic acid‐induced hepatotoxicity in Alpers syndrome is associated with mitochondrial permeability transition pore opening‐dependent apoptotic sensitivity in an induced pluripotent stem cell model. Hepatology, 61(5):1730-1739.
12. Chen,K.,Long,Q.,Xing,G.,…Pei,D*& Liu,X*. (2020). Heterochromatin loosening by the Oct4 linker region facilitates Klf4 binding and iPSC reprogramming. EMBO Journal,39(1):e99165 (F1000推荐)
13. Liao,R.,Wu,Y.,Le,Q.,… Liu,X* & Li,P*. (2023). BCL11B and the NuRD complex cooperatively guard T-cell fate and inhibit OPA1-mediated mitochondrial fusion in T cells. EMBO Journal,2023 Nov 2;42(21):e113448.
14. Xiang,G.,Yang,L.,Long,Q.,…Liu,X*. (2017). BNIP3L-dependent mitophagy accounts for mitochondrial clearance during 3 factors-induced somatic cell reprogramming. Autophagy,13(9):1543-1555.
15. Zhou,Y.,Long,Q.,Wu,H.,…Liu,X*. (2020). Topology-dependent,bifurcated mitochondrial quality control under starvation. Autophagy,16(3):562-574. (封面)
16. Wu, Y.,Chen, K.,Li L.,…Liu,X*. (2022). Plin2-mediated lipid droplet mobilization accelerates exit from pluripotency by lipidomic remodeling and histone acetylation. Cell Death & Differentiation, 29(11):2316-2331.
17. Xing, G.,Liu, Z.,Huang L.,…Pei,D* Liu,X* & Chen,K*. (2022). MAP2K6 remodels chromatin and facilitates reprogramming by activating Gatad2b-phosphorylation dependent heterochromatin loosening. Cell Death & Differentiation, 29(5):1042-1054.
18. Yao,D.,Li,Y.,Zeng,S.,…Liu,X*. (2022). Short-form OPA1 is a molecular chaperon in mitochondrial intermembrane space. Science China-Life Sciences, 65(2):227-235. (封面).
19. Wang,R.,Bao,F.,Lu,M.,…Zhang,Q.*,Liu,X*. (2024). MSC-mediated mitochondrial transfer restores mitochondrial DNA and function in neural progenitor cells of Leber's Hereditary Optic Neuropathy. Science China-Life Sciences, Jul 24,2024  https://doi.org/10.1007/s11427-024-2647-8
20. Yang,L.,Lin,X.,Tang,H.,....Liu,X*. (2020).  Mitochondrial DNA mutation exacerbates female reproductive aging via impairment of the NADH/NAD⁺ redox. Aging Cell 19(9):e13206.
21. Bao,F.,Shi,H.,Gao,M.,…Liu,X*. (2018). Polybrene induces neural degeneration by bidirectional Ca²⁺ influx dependent mitochondrial and ER-mitochondrial dynamics. Cell Death & Disease,9(10):966.
22. Li,L.,Chen,K.,Wu Y.,...Liu,X*. (2017). Gadd45a opens up the promoter regions of miR-295 facilitating pluripotency induction. Cell Death & Disease,8(10):e3107.
23. Lin,Y.,Xiao,M.,Chen,H.,Meng,Y.,Zhao,N.,Yang,L.,Tang,H.,Wang,J.,Liu,X*,Zhu,Y.*,Zhuang,S.*. (2019). A novel mitochondrial micropeptide MPM enhances mitochondrial respiratory activity and promotes myogenic differentiation. Cell Death & Disease,10(7):528
24. Yang,L.,Long,Q.,Liu,J.,...Liu,X*. (2015). Mitochondrial fusion provides an ‘initial metabolic complementation’ controlled by mtDNA. Cellular and Molecular Life Sciences, 72(13):2585-2598. 
25. Chen,K.,Long,Q.,Wang,T.,… Liu,X* & Pei,D*. (2016). Gadd45a is a heterochromatin relaxer that enhances iPS cell generation. EMBO Reports,17(11):1641-1656.
26. Bao,F.,Shi,H.,Long,Q.,…Liu,X*. (2016). Mitochondrial membrane potential-dependent endoplasmic reticulum fragmentation is an important step in neuritic degeneration. CNS Neuroscience & Therapeutics, 22(8):648-660.  (封面)
27. Yang,L.,Tang,H.,Lin,X....Liu,X*. (2020). OPA1-Exon4b binds to mtDNA D-loop for transcriptional and metabolic modulation,independent of mitochondrial fusion. Frontiers in Cell and Developmental Biology, 8: 180.
28. Wu,Y.,Chen,K.,Liu,X.,...Liu,X*. (2015). Srebp‐1 Interacts with c‐Myc to Enhance Somatic Cell Reprogramming. Stem Cells, 34(1):83-92.
29. Long,Q.,Zhao,D.,Fan,W.,...Wang X* & Liu,X*. (2015). Modeling of mitochondrial donut formation. Biophysical Journal, 109(5):892-899.
30. Liu,W.,Long,Q.,Chen,K.,...& Liu,X*. (2013). Mitochondrial metabolism transition cooperates with nuclear reprogramming during induced pluripotent stem cell generation. Biochemical and Biophysical Research Communications, 431(4),767-771.
31. Wu,Y.,Liu,Y.,Hao,Z.,Liu,X*. (2022). NAD+ is critical for maintaining acetyl-CoA and H3K27ac in embryonic stem cells by Sirt1-dependent deacetylation of AceCS1. Life Medicine,1(3),401-405. (Most Picked Paper Award)
32. Tang,H.,Hu,Z.,Yang,L.,...& Liu,X*. (2022). OPA1-Exon4b modulates the migration and invasion of hepatocellular carcinoma cells by ATP regulation. Mitochondrial Communications, 1,16-22
33. Qi,J.,Long,Q.,Yuan Y.,…& Liu,X*. (2023). Mitochondrial DNA mutation affects the pluripotency of embryonic stem cells through modulating metabolism,Genome Instability & Disease,4(1), 12–20.
34. Liu,X., Weaver,D.,Shirihai,O.,& Hajnóczky,G. (2009). Mitochondrial ‘kiss‐and‐run’:interplay between mitochondrial motility and fusion–fission dynamics. The EMBO Journal, 28(20),3074-3089. (F1000推荐)
35. Liu,X.,& Hajnoczky,G. (2011). Altered fusion dynamics underlie unique morphological changes in mitochondria during hypoxia–reoxygenation stress. Cell Death & Differentiation, 18(10),1561-1572. (F1000推荐)
36. Weaver,D.,Eisner,V., Liu,X.,… & Hajnóczky,G. (2014). Distribution and apoptotic function of outer membrane proteins depend on mitochondrial fusion. Molecular Cell, 54(5),870-878. (co-first author)