2009年博士毕业于中国科学院上海生物化学与细胞生物学研究所,美国加州大学洛杉矶分校(UCLA)博士后;回国后在中国科学院上海生物化学与细胞生物学先后担任助理研究员、副研究员。2018年9月入职中国科学院广州生物医药与健康研究院,担任研究员、课题组长、博士生导师。为国家重点高层次青年人才,广东省杰青,中国发育生物学专业委员会副秘书长,谱系技术与装备研究中心执行副主任。
国际干细胞学会(ISSCR)会员
中国动物学会发育生物学专业委员会副秘书长
Sanofi-SIBS 2017 Distinguished Young Faculty
ISSCR 2017 Poster Award and Travel Award
国家级人才项目
中国生命科学十大进展
中国生物信息学十大进展
2025
1. Chen,C.,Liao,Y.,Zhu,M.,Wang,L.,Yu,X.,Li,M.,Peng,G.*,2025. Dual-nuclease single-cell lineage tracing by Cas9 and Cas12a. Cell Reports 44,115105.
2. Meng,X.,Li,W.,Xu,J.,Yao,Y.,Gong,A.,Yang,Y.,Qu,F.,Guo,C.,Zheng,H.,Cui,G.*,Suo,S.*,Peng,G.*,2025. Spatiotemporal transcriptome atlas of developing mouse lung. Science Bulletin S2095927325002403.
3. Zhang,G.,Zhang,X.,Pan,W.,Chen,X.,Wan,L.,Liu,C.,Yong,Y.,Zhao,Y.,Sang,S.,Zhang,L.,Yao,S.,Guo,Y.,Wang,M.,Wang,X.,Peng,G.*,Yan,X.*,Wang,Y.*,Zhang,M.*,2025. Dissecting the Spatial and Single‐Cell Transcriptomic Architecture of Cancer Stem Cell Niche Driving Tumor Progression in Gastric Cancer. Advanced Science 2413019.
4. Guo,C.-K.,Xia,C.-R.,Peng,G.*,Cao,Z.-J.*,Gao,G.*,2025. Learning Phenotype Associated Signature in Spatial Transcriptomics withPASSAGE. Small Methods e2401451.
2024
5. Jiang,F.,Wang,H.,Li,Z.,Cui,G.,Peng,G.*,2024. Leveraging spatial multiomics to unravel tissue architecture in embryo development. Trends in Genetics S0168952524002713. (Review)
6. Fan,Y.,Bian,X.,Meng,X.,Li,L.,Fu,L.,Zhang,Yanan,Wang,L.,Zhang,Yan,Gao,D.,Guo,X.,Lammi,M.J.,Peng,G.*,Sun,S.*,2024. Unveiling inflammatory and prehypertrophic cell populations as key contributors to knee cartilage degeneration in osteoarthritis using multi-omics data integration. Annals of the Rheumatic Diseases 83,926–944.
7. Wang,Z.,Li,Z.,Luan,T.,Cui,G.,Shu,S.,Liang,Y.,Zhang,K.,Xiao,J.,Yu,W.,Cui,J.,Li,A.*,Peng,G.*,Fang,Y.*,2024. A spatiotemporal molecular atlas of mouse spinal cord injury identifies a distinct astrocyte subpopulation and therapeutic potential of IGFBP2. Developmental Cell 59,2787-2803.e8.
8. Zou,S.,Peng,G.*,Ma,Z.*,2024. Surface-Functionalizing Strategies for Multiplexed Molecular Biosensing: Developments Powered by Advancements in Nanotechnologies. Nanomaterials. (Review)
2023
9. Qu,F.,Li,W.,Xu,J.,Zhang,R.,Ke,J.,Ren,X.,Meng,X.,Qin,L.,Zhang,J.,Lu,F.,Zhou,X.,Luo,X.,Zhang,Z.,Wang,M.,Wu,G.,Pei,D.,Chen,J.,Cui,G.*,Suo,S.*,Peng,G.*,2023. Three-dimensional molecular architecture of mouse organogenesis. Nat Commun 14,4599.
10. Jiang,F.,Zhou,X.,Qian,Y.,Zhu,M.,Wang,L.,Li,Z.,Shen,Q.,Wang,M.,Qu,F.,Cui,G.,Chen,K.,Peng,G.*,2023. Simultaneous profiling of spatial gene expression and chromatin accessibility during mouse brain development. Nat Methods 20,1048–1057.
11. Xu,H.J.,Yao,Y.,Yao,F.,Chen,J.,Li,M.,Yang,X.,Li,S.,Lu,F.,Hu,P.,He,S.*,Peng,G.*,Jing,N.*,2023. Generation of functional posterior spinal motor neurons from hPSCs-derived human spinal cord neural progenitor cells. Cell Regen 12,15.
12. Meng,X.,Cui,G.*,Peng,G.*,2023. Lung development and regeneration: newly defined cell types and progenitor status. Cell Regen 12,5. (Review)
2022
13. Chen,C.,Liao,Y.,Peng,G.*,2022. Connecting past and present: single-cell lineage tracing. Protein Cell 13,790–807. (Review)
14. Cui,G.,Feng,S.,Yan,Y.,Wang,L.,He,X.,Li,X.,Duan,Y.,Chen,J.,Tang,K.,Zheng,P.,Tam,P.P.L.,Si,W.,Jing,N.,Peng,G.*,2022. Spatial molecular anatomy of germ layers in the gastrulating cynomolgus monkey embryo. Cell Reports 40,111285.
15. Wen,L.,Li,G.,Huang,T.,Geng,W.,Pei,H.,Yang,J.,Zhu,M.,Zhang,P.,Hou,R.,Tian,G.,Su,W.,Chen,J.,Zhang,D.,Zhu,P.,Zhang,W.,Zhang,X.,Zhang,N.,Zhao,Y.*,Cao,X.*,Peng,G.*,Ren,X.*,Jiang,N.*,Tian,C.*,Chen,Z.-J.*,2022. Single-cell technologies: From research to application. The Innovation 3,100342. (Review)
16. Li,Z.,Peng,G.*,2022. Spatial transcriptomics: new dimension of understanding biological complexity. Biophysics Reports 8,119–135. (Review)
2021
17. Lin,J.,Wu,S.,Shen,Q.,Liu,J.,Huang,S.,Peng,G.*,Qiao,Y.*,2021. Base editing‐mediated perturbation of endogenous PKM1/2 splicing facilitates isoform‐specific functional analysis in vitro and in vivo. Cell Proliferation 54,e13096.
18. Xia,Q.,Cui,G.,Fan,Y.,Wang,X.,Hu,G.,Wang,L.,Luo,X.,Yang,L.,Cai,Q.,Xu,K.,Guo,W.,Gao,M.,Li,Y.,Wu,J.,Li,W.,Chen,J.,Qi,H.,Peng,G.*,Yao,H.*,2021. RNA helicase DDX5 acts as a critical regulator for survival of neonatal mouse gonocytes. Cell Proliferation 54,e13000.
2020
19. Peng,G.*,Cui,G.,Ke,J.,Jing,N.*,2020. Using Single-Cell and Spatial Transcriptomes to Understand Stem Cell Lineage Specification During Early Embryo Development. Annu. Rev. Genom. Hum. Genet. 21,163–181. (Review)
2019
20. Liu,Q.,Liu,K.,Cui,G.,Huang,X.,Yao,S.,Guo,W.,Qin,Z.,Li,Y.,Yang,R.,Pu,W.,Zhang,L.,He,L.,Zhao,H.,Yu,W.,Tang,M.,Tian,X.,Cai,D.,Nie,Y.,Hu,S.,Ren,T.,Qiao,Z.,Huang,H.,Zeng,Y.A.,Jing,N.,Peng,G.*,Ji,H.*,Zhou,B.*,2019. Lung regeneration by multipotent stem cells residing at the bronchioalveolar-duct junction. Nat Genet 51,728–738.
21. Peng,G.*,Suo,S.,Cui,G.,Yu,F.,Wang,R.,Chen,J.,Chen,S.,Liu,Z.,Chen,G.,Qian,Y.,Tam,P.P.L.,Han,J.-D.J.*,Jing,N.*,2019. Molecular architecture of lineage allocation and tissue organization in early mouse embryo. Nature 572,528–532.
完整论文情况Google scholar: https://scholar.google.com/citations?user=s7XddBgAAAAJ