2006.09-2009.06，南京农业大学，国家生物学理科基地，理学学士

2009.09-2014.06，中国科学院广州生物医药与健康研究院，生物化学与分子生物学，理学博士

2014.08-2017.12 中国科学院广州生物医药与健康研究院，华南干细胞与再生医学研究所，助理研究员

2018.1 至今，中国科学院广州生物医药与健康研究院，华南干细胞与再生医学研究所，副研究员

1.    多能性建立与维持的分子机制

2.    利用单细胞测序技术研究细胞命运决定

1.Chen, J.*, Guo, L.*, Zhang, L.*, Wu, H., Yang, J., Liu, H., Wang, X., Hu, X., Gu, T., Zhou, Z., Liu, J., Liu, J., Wu, H., Mao, S.Q., Mo, K., Li, Y., Lai, K., Qi, J., Yao, H., Pan, G., Xu, G.L., and Pei, D. Vitamin C modulates TET1 function during somatic cell reprogramming. Nat Genet, 2013. 45(12): 1504-1509. (*共同第一作者)

2.Chen, Y.*, Guo, L.*, Chen, J.*, Zhao, X., Zhou, W., Zhang, C., Wang, J., Jin, L., Pei, D., and Zhang, F. Genome-wide CNV analysis in mouse induced pluripotent stem cells reveals dosage effect of pluripotent factors on genome integrity. BMC Genomics, 2014. 1579.

3. 郭琳，陈捷凯，裴端卿，维生素C与表观遗传调控，科学通报，2014, 59 (28) :2833-2839

4.Li, D.*, Liu, J.*, Yang, X.*, Zhou, C., Guo, J., Wu, C., Qin, Y., Guo, L., He, J., Yu, S., Liu, H., Wang, X., Wu, F., Kuang, J., Hutchins, A.P., Chen, J., and Pei, D. Chromatin Accessibility Dynamics during iPSC Reprogramming. Cell Stem Cell, 2017. 21(6): 819-833 e816.

5.Chen, J.*, Liu, H.*, Liu, J., Qi, J., Wei, B., Yang, J., Liang, H., Chen, Y., Chen, J., Wu, Y., Guo, L., Zhu, J., Zhao, X., Peng, T., Zhang, Y., Chen, S., Li, X., Li, D., Wang, T., and Pei, D. H3K9 methylation is a barrier during somatic cell reprogramming into iPSCs. Nat Genet, 2013. 45(1): 34-42.

6.Chen, J.*, Liu, J.*, Chen, Y., Yang, J., Chen, J., Liu, H., Zhao, X., Mo, K., Song, H., Guo, L., Chu, S., Wang, D., Ding, K., and Pei, D. Rational optimization of reprogramming culture conditions for the generation of induced pluripotent stem cells with ultra-high efficiency and fast kinetics. Cell Res, 2011. 21(6): 884-894.