教育经历：

2003.09－2007.06：华南师范大学，生命科学学院，理学学士

工作经历：

2023.01至今：中国科学院广州生物医药与健康研究院，高级实验师

2007.08-2022.12：中国科学院广州生物医药与健康研究院，助理研究员

1、胚胎工程与动物克隆

2、显微操作技术应用

1、 国家重点研发计划,代谢紊乱条件性敲除猪模型的建立及发病机理研究,2022-01 至 2026-12,280万元,在研,参与

2、海南省重大科技计划项目,五指山猪实验动物模式化研究,2021-12 至 2024-12,200万元,在研,参与

3、广州市科技计划项目,基因编辑猪重大脑疾病模型的制备与研究,2020-04 至 2023-03,1000万元,在研,参与

4、国家自然科学基金委员会,联合基金项目,基于人多能干细胞及器官缺陷猪模型进行人源 心脏异种再造的研究,2024-01-01 至 2027-12-31,262万元,在研,参与

1、大动物基因修饰技术研究及基因修饰动物模型的建立,广州市人民政府,广州市科学技术进步奖一等奖,2015(赖良学;樊娜娜;杨化强;赵本田;欧阳振;刘朝明;赵宇;杨东山;邓为;黄黎珍;肖磊;顾为望) (科研奖励)

2、猪基因突变技术创新及基因修饰猪模型的建立,广东省人民政府,科技进步,省部一等奖,2016(赖良学;樊娜娜;杨化强;顾为望;肖磊;杜玉涛;黄黎珍;陈霁君;商周春;杨东山;赵本田;

欧阳振;刘朝明;赵宇;邓为) (科研奖励)

1. Degong Ruan #,Jiangyun Peng#,Xiaoshan Wang #, Zhen Ouyang #,Qingjian Zou,Yi Yang,Fangbing Chen,Weikai Ge,Han Wu,Zhaoming Liu,Yu Zhao,Bentian Zhao,Quanjun Zhang,Chengdan Lai,Nana Fan,Zhiwei Zhou,Qishuai Liu,Nan Li,Qin Jin,Hui Shi,Jingke Xie,Hong Song,Xiaoyu Yang,Jiekai Chen,Kepin Wang *,Xiaoping Li *,Liangxue Lai*. XIST Derepression in Active X Chromosome Hinders Pig Somatic Cell Nuclear Transfer. Stem Cell Reports. 2018 Feb 13;10(2):494–508.IF:7.294

2. Qingjian Zou#,Xiaomin Wang#,Yunzhong Liu#, Zhen Ouyang#,Haibin Long,Shu Wei,Jige Xin,Bentian Zhao,Sisi Lai,Jun Shen,Qingchun Ni,Huaqiang Yang,Huilin Zhong,Li Li,Minhua Hu,Quanjun Zhang,Zhidong Zhou,Jiaxin He,Quanmei Yan,Nana Fan,Yu Zhao,Zhaoming Liu,Lin Guo,Jiao Huang,Guanguan Zhang,Jun Ying*,Liangxue Lai*,Xiang Gao*. Generation of gene-target dogs using CRISPR/Cas9 system. Journal of Molecular Cell Biology,Volume 7,Issue 6,December 2015,Pages 580–583.IF:8.185

3. 欧阳振.邱杨.吴嘉妮.余瑶章.龚莉红.李海航. 几种天然材料对茶多酚和咖啡因的吸附与分离特性. 科技导报. 2009,27(08)

非第一作者论文

1. Yanhui Liang,Jingke Xie,Quanjun Zhang,Xiaomin Wang,Shixue Gou,Lihui Lin,Tao Chen,Weikai Ge,Zhenpeng Zhuang,Meng Lian,Fangbing Chen,Nan Li,Zhen Ouyang,Chengdan Lai,Xiaoyi Liu,Lei Li,Yinghua Ye,Han Wu,Kepin Wang,and Liangxue Lai. AGBE: a dual deaminase-mediated base editor by fusing CGBE with ABE for creating a saturated mutant population with multiple editing patterns. Nucleic Acids Res. 2022 May 20;50(9):5384–5399. IF:19.16

2. Yanling Zhu,Zhishuai Zhang,Nana Fan,Ke Huang,Hao Li,Jiaming Gu,Quanjun Zhang,Zhen Ouyang,Tian Zhang,Jun Tang,Yanqi Zhang,Yangyang Suo,Chengdan Lai,Jiaowei Wang,Junwei Wang,Yongli Shan,Mingquan Wang,Qianyu Chen,Tiancheng Zhou,Liangxue Lai.Guangjin Pan. Generating functional cells through enhanced interspecies chimerism with human pluripotent stem cells. Stem Cell Reports. 2022 May 10;17(5):1059–1069. IF:7.294

3. Sen Yan,Zhuchi Tu,Zhaoming Liu,Nana Fan,Huiming Yang,Su Yang,Weili Yang,Yu Zhao,Zhen Ouyang,Chengdan Lai,Huaqiang Yang,Li Li,Qishuai Liu,Hui Shi,Guangqing Xu,Heng Zhao,Hongjiang Wei,Zhong Pei,Shihua Li,Liangxue Laiand Xiao-Jiang Li. Cell. 2018 May 3;173(4):989–1002.e13.IF: 66.85

4. Xiaoqing Zhou,Jige Xin,Nana Fan,Qingjian Zou,Jiao Huang,Zhen Ouyang,Yu Zhao,Bentian Zhao,Zhaoming Liu,Sisi Lai,Xiaoling Yi,Lin Guo,Miguel A Esteban,Yangzhi Zeng,Huaqiang Yang,Liangxue Lai. Generation of CRISPR/Cas9-mediated gene-targeted pigs via somatic cell nuclear transfer. Cellular and Molecular Life Sciences volume 72,pages1175–1184 (2015) .IF: 9.207 

5. Dongshan Yang,Huaqiang Yang,Wei Li,Bentian Zhao,Zhen Ouyang,Zhaoming Liu,Yu Zhao,Nana Fan,Jun Song,Jiangtian Tian,Feng Li,Jifeng Zhang,Lin Chang,Duanqing Pei,Y Eugene Chen,Liangxue Lai. Generation of PPARγ mono-allelic knockout pigs via zinc-finger nucleases and nuclear transfer cloning. Cell Research volume 21,pages979–982 (2011).IF: 46.297